Our research activities focus on the development of innovative analytical platforms and incorporate aspects of diverse disciplines ranging from bioengineering to nanotechnology and chemical biology.
Triplex DNA clamp regulates Cas12a activation for ssDNA and RNA sensing
Di Pede, A.C., Bagheri, N., Belforte, E., Palone, A., Rossetti, M., Porchetta, A., (2026) Nucleic Acids Research, 54(1), p.gkaf1392
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Synthetic DNA Transducers Integrate DNA Repair to CRISPR Signal Transduction
Bagheri, N., Bertucci, A., Merlo, R. and Porchetta, A., (2026) ACS Sensors, 11, 1634-1644
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PAM-Engineered Toehold Switches as Input-Responsive Activators of CRISPR-Cas12a for Sensing Applications
Bagheri, N., Chamorro, A., Idili, A., Porchetta, A.* (2024). Angew. Chem. Int. Ed. 63(17), 29:e202319677.
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Our research group provides highly multi- and interdisciplinary training opportunity for the next generation of chemists working at the forefront of bioengineering and analytical chemistry. We aim at creating an environment that reflects the value of respects, diversity, and inclusion.












